Abstract
We examined nasopharyngeal pneumococcal colonization density patterns surrounding acute respiratory illnesses (ARI) in young children in Peru. Pneumococcal densities were dynamic, gradually increasing leading up to an ARI, peaking during the ARI, and decreasing after the ARI. Rhinovirus co-infection was associated with higher pneumococcal densities.
Keywords:
Peru; Streptococcus pneumoniae; acute respiratory illnesses; bacteria; bacterial load; nasopharynx; pneumococcal density; pneumococcal infections; pneumococcal pneumonia; respiratory tract infections; young children.
MeSH terms
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Acute Disease
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Bacterial Load
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Child, Preschool
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Cross-Sectional Studies
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Female
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Humans
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Infant
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Infant, Newborn
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Male
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Nasopharynx / microbiology*
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Peru / epidemiology
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Pneumococcal Infections / epidemiology*
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Pneumococcal Infections / microbiology*
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Pneumococcal Infections / prevention & control
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Pneumococcal Vaccines / immunology
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Population Surveillance
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Respiratory Tract Infections / epidemiology*
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Respiratory Tract Infections / microbiology*
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Respiratory Tract Infections / prevention & control
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Risk Factors
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Streptococcus pneumoniae / immunology
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Streptococcus pneumoniae / isolation & purification*