Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010)

M López; A Rueda; J P Florido; L Blasco; E Gato; L Fernández-García; L Martínez-Martínez; F Fernández-Cuenca; J Pachón; J M Cisneros; J Garnacho-Montero; J Vila; J Rodríguez-Baño; A Pascual; G Bou; M Tomás

doi:10.1128/genomeA.01182-16

Genomic Evolution of Two Acinetobacter baumannii Clinical Strains from ST-2 Clones Isolated in 2000 and 2010 (ST-2_clon_2000 and ST-2_clon_2010)

Genome Announc. 2016 Oct 20;4(5):e01182-16. doi: 10.1128/genomeA.01182-16.

Authors

M López^{1

2}, A Rueda³, J P Florido³, L Blasco¹, E Gato^{1

2}, L Fernández-García¹, L Martínez-Martínez^{4

5

2}, F Fernández-Cuenca^{6

2}, J Pachón^{7

2}, J M Cisneros^{7

2}, J Garnacho-Montero^{6

8}, J Vila^{8

2}, J Rodríguez-Baño^{6

2}, A Pascual^{6

2}, G Bou^{1

2}, M Tomás^{9

2}

Affiliations

¹ Department of Microbiology, Complejo Hospitalario Universitario, A Coruña, INIBIC, La Coruña, Spain.
² Spanish Network for the Research in Infectious Diseases (REIPI RD12/0015), Seville, Spain.
³ Bioinformatics, GBPA, Seville, Spain.
⁴ Department of Clinical Microbiology, Hospital Universitario Marqués de Valdecilla-IFIMAV, Santander, Spain.
⁵ Departament of Molecular Biology, University of Cantabria, Santander, Spain.
⁶ Unidad Intercentros de Enfermedades Infecciosas, Microbiología y Medicina Preventiva, Hospital Universitario Virgen Macarena, Seville, Spain.
⁷ Institute of Biomedicine of Seville (IBiS), University Hospital Virgen del Rocío/CSIC/University of Seville, Seville, Spain.
⁸ Department of Clinical Microbiology, Hospital Clínic, School of Medicine, University of Barcelona, Barcelona and ISGlobal, Barcelona Centre for International Health Research (CRESIB), Hospital Clínic, Barcelona, Spain.
⁹ Department of Microbiology, Complejo Hospitalario Universitario, A Coruña, INIBIC, La Coruña, Spain ma.del.mar.tomas.carmona@sergas.es.

Abstract

Acinetobacter baumannii is a successful nosocomial pathogen due to its ability to persist in hospital environments by acquiring mobile elements such as transposons, plasmids, and phages. In this study, we compared two genomes of A. baumannii clinical strains isolated in 2000 (ST-2_clon_2000) and 2010 (ST-2_clon_2010) from GenBank project PRJNA308422.

Grants and funding

This study was funded by grants PI10/00056 and PI13/02390 awarded to M. Tomás within the State Plan for R+D+I 2013-2016 (National Plan for Scientific Research, Technological Development and Innovation 2008-2011). It was cofinanced by the ISCIII-Deputy General Directorate of Evaluation and Promotion of Research-European Regional Development Fund “A Way of Making Europe” and the Instituto de Salud Carlos III FEDER, Spanish Network for Research in Infectious Diseases (REIPI RD12/0015). M. Tomás was financially supported by the Miguel Servet Research Programme (C.H.U.A. Coruña and ISCIII).