Anaphylaxis to Over-the-Counter Flurbiprofen in a Child

Pharmacology. 2017;99(3-4):121-123. doi: 10.1159/000452671. Epub 2016 Nov 11.

Abstract

Non-steroidal anti-inflammatory drugs are suspected to cause drug hypersensitivity very frequently in paediatric patients. In this article, we describe the first case of anaphylaxis to flurbiprofen in a child and provide insight into the possibility of severe reactions and even anaphylaxis to over-the-counter flurbiprofen. Finally, the importance of a rigorous allergy work-up in reaching a confident diagnosis and providing the patient with a safe alternative is shown.

Publication types

  • Case Reports

MeSH terms

  • Anaphylaxis / chemically induced*
  • Anaphylaxis / diagnosis*
  • Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
  • Child
  • Female
  • Flurbiprofen / adverse effects*
  • Humans
  • Nonprescription Drugs / adverse effects*

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Nonprescription Drugs
  • Flurbiprofen