•A multi-layer technique for reconstruction after pelvic exenteration is proposed.•Human acellular dermal matrix used in reconstruction after total pelvic exenteration.•A reconstructive technique based on human dermis, omental flap and fat is proposed.
Keywords: Cervical cancer; Human acellular dermal matrix; Lipofilling; Omental flap; Pelvic exenteration; Pelvic reconstruction.