Data on clinical characteristics of a heart failure patients' cohort with reduced ejection fraction and analysis of the circulating values of five different heart failure biomarkers; high sensitivity troponin T, galectin-3, C-terminal propeptide of type I procollagen, soluble AXL and BNP

M Batlle; B Campos; M Farrero; M Cardona; B González; M A Castel; J Ortiz; E Roig; M J Pulgarín; J Ramírez; J L Bedini; M Sabaté; P García de Frutos; F Pérez-Villa

doi:10.1016/j.dib.2016.10.020

Data on clinical characteristics of a heart failure patients' cohort with reduced ejection fraction and analysis of the circulating values of five different heart failure biomarkers; high sensitivity troponin T, galectin-3, C-terminal propeptide of type I procollagen, soluble AXL and BNP

Data Brief. 2016 Nov 3:9:876-882. doi: 10.1016/j.dib.2016.10.020. eCollection 2016 Dec.

Authors

M Batlle¹, B Campos², M Farrero³, M Cardona³, B González⁴, M A Castel³, J Ortiz³, E Roig⁵, M J Pulgarín¹, J Ramírez⁶, J L Bedini⁴, M Sabaté¹, P García de Frutos⁷, F Pérez-Villa³

Affiliations

¹ Institute of Biomedical Research August Pi i Sunyer (IDIBAPS) and the Cardiovascular Clinic Institute, Hospital Clínic de Barcelona, Spain.
² Department of Public Health, Universitat de Barcelona, Spain.
³ Heart Failure and Transplant Unit, Cardiovascular Clinic Institute, Hospital Clínic de Barcelona and researcher at Institute of Biomedical Research August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
⁴ Core Laboratory, Hospital Clínic de Barcelona, Spain.
⁵ Heart Failure Unit at the Cardiology Department, Hospital de la Santa Creu i Sant Pau, Institut de Recerca Biomèdica (IIB Sant Pau), Universitat Autònoma de Barcelona, Barcelona, Spain.
⁶ Pathological Anatomy Department, Hospital Clínic de Barcelona, Spain.
⁷ Department of Cell Death and Proliferation at Institut d´Investigacions Biomèdiques de Barcelona (IIBB-CSIC) and IDIBAPS, Barcelona, Spain.

Abstract

In this article, the full description of a heart failure with reduced ejection fraction (HF_REF) cohort of 192 patients is provided. Tables with the baseline demographic, prior history, ECG parameters, echocardiographic parameters, laboratory values and pharmacological treatment of these patients are included. Also, the quartile values of the analyzed circulating biomarkers: high sensitivity Troponin T (hs-TnT), galectin-3 (Gal-3), C-terminal propeptide of type I procollagen (CICP), soluble AXL (sAXL) and Brain Natriuretic Peptide (BNP) are given. The main demographic and clinical features of the patients' subgroups that have hs-TnT, Gal-3, CICP or BNP above the third quartile are described. Tables with Pearson correlation analysis of the HF_REF patients' biomarker levels are included. And Pearson correlation analysis of the HF_REF patients' hs-TnT, Gal-3, CICP levels with patients' biochemical parameters, blood count and inflammation parameters are also described. These data are related to the research articles (AXL receptor tyrosine kinase is increased in patients with heart failure (M. Batlle, P. Recarte-Pelz, E. Roig, M.A. Castel, M. Cardona, M. Farrero, et al., 2014) [1] and Use of serum levels of high sensitivity troponin T, galectin-3 and C-terminal propeptide of type I procollagen at long term follow-up in Heart Failure patients with reduced ejection fraction: comparison with soluble AXL and BNP (M. Batlle, B. Campos, M. Farrero, M. Cardona, B. González, M.A. Castel, et al., 2016) [2].

Keywords: AXL receptor tyrosine kinase; Brain Natriuretic Peptide; C-terminal propeptide of type I procollagen; Galectin-3; Heart failure; High sensitivity troponin T.