Pitfalls in the detection of N-methyl-d-aspartate-receptor (NMDA-R) antibodies

Clin Biochem. 2017 Apr;50(6):354-355. doi: 10.1016/j.clinbiochem.2016.11.023. Epub 2016 Nov 23.

Authors

Matteo Gastaldi¹, Anaïs Thouin², Diego Franciotta³, Angela Vincent⁴

Affiliations

¹ IRCCS, C. Mondino National Neurological Institute, Pavia, Italy; University of Pavia, Pavia, Italy. Electronic address: matteo.gastaldi@mondino.it.
² Insitute of Neuroscience, University of Newcastle, Newcastle upon Tyne, UK.
³ IRCCS, C. Mondino National Neurological Institute, Pavia, Italy.
⁴ Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.

PMID: 27889566
DOI: 10.1016/j.clinbiochem.2016.11.023

No abstract available

Keywords: Autoimmune encephalitis; Cell-based assay; N-Methyl-d-aspartate receptor antibodies.

Publication types

Letter

MeSH terms

Autoantibodies / analysis*
Autoimmune Diseases / blood
Autoimmune Diseases / diagnosis
Autoimmune Diseases / immunology
Encephalitis / blood
Encephalitis / diagnosis
Encephalitis / immunology
False Positive Reactions
HEK293 Cells
Humans
Lab-On-A-Chip Devices
Protein Subunits / antagonists & inhibitors
Protein Subunits / genetics
Protein Subunits / metabolism
Quality Control
Reagent Kits, Diagnostic
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors*
Receptors, N-Methyl-D-Aspartate / genetics
Receptors, N-Methyl-D-Aspartate / metabolism
Recombinant Proteins / chemistry
Recombinant Proteins / metabolism

Substances

Autoantibodies
Protein Subunits
Reagent Kits, Diagnostic
Receptors, N-Methyl-D-Aspartate
Recombinant Proteins