Management of Trauma-Induced Coagulopathy with Thrombelastography

Eduardo Gonzalez; Ernest E Moore; Hunter B Moore

doi:10.1016/j.ccc.2016.09.002

Management of Trauma-Induced Coagulopathy with Thrombelastography

Crit Care Clin. 2017 Jan;33(1):119-134. doi: 10.1016/j.ccc.2016.09.002.

Authors

Eduardo Gonzalez¹, Ernest E Moore², Hunter B Moore¹

Affiliations

¹ Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA.
² Department of Surgery, University of Colorado, 12700 East 19th Avenue, Denver, CO 80045, USA; Department of Surgery, Denver Health Medical Center, 77 Bannock Street, Denver, CO 80204, USA; Editorial office, Journal of Trauma and Acute Care Surgery, 655 Broadway, Suite 365, Denver, CO 80203, USA. Electronic address: ernest.moore@dhha.org.

Abstract

Viscoelastic assays, such as thrombelastography (TEG) and rotational thrombelastometry (ROTEM), have emerged as point-of-care tools that can guide the hemostatic resuscitation of bleeding injured patients. This article describes the role of TEG in contemporary trauma care by explaining this assay's methodology, clinical applications, and result interpretation through description of supporting studies to provide the reader with an evidence-based user's guide. Although TEG and ROTEM are assays based on the same viscoelastic principle, this article is focused on data supporting the use of TEG in trauma, because it is available in trauma centers in North America; ROTEM is mostly available in Europe.

Keywords: Coagulopathy; Fibrinolysis; Resuscitation; TEG; Thrombelastography; Transfusion.

Publication types

Review

MeSH terms

Blood Coagulation Disorders / etiology*
Blood Coagulation Disorders / therapy*
Europe
Humans
North America
Practice Guidelines as Topic*
Thrombelastography / standards*
Wounds and Injuries / complications*
Wounds and Injuries / diagnosis
Wounds and Injuries / therapy*

Abstract

Publication types

MeSH terms

Grants and funding