Angiosarcoma following radiation therapy for breast cancer Case report

Ann Ital Chir. 2016 Dec 20:5:S2239253X16025032.

Abstract

More and better accessibility to screening and increasing women's knowledge about the main symptomatic breast cancer signs result in detection of this neoplasm at an early stage, allowing a conservative surgical treatment. Breast conserving therapy (BCT) due to breast carcinoma involves the use of adjuvant radiotherapy which carries a risk the secondary radiation-induced malignancy. Angiosarcoma of the breast is an extremely rare radiation-induced malignant tumor following breast conserving therapy (BCT), first described by Schmidt in 1887. In this article the authors presented the case of a 56-year-old woman who was admitted to the hospital because of diagnosed angiosarcoma of the right breast after breast conserving therapy (BCT) with the Sentinel Node Biopsy (SNB) and adjuvant radiotherapy of her breast carcinoma 5 years earlier. The patient had a simple mastectomy performed and on the second day after surgery was discharged home.

Key words: Angiosarcoma, Breast cancer, Radiation therapy, Surgery, Treatment.

La migliorata disponibilità agli screening preventive e la maggiore consapevolezza delle donne riguardo I prinipali segni sintomatici del cancro della mammilla hanno determinate la scoperta di questa neoplasia in stadi più precoci, consentendo l’adozione del trattamento chirurgico conservative. Il trattamento conservativo della mammella (BCT) prevede il trattamento radioterapico adiuvante, che comporta il rischio di indurre tumori secondari indotti dalla radiazione. L’angiosarcoma della mammella è un tumore maligno estremamente raro indotto dall’energia radiante dopo trattamento conservativo della mammella (BCT) descritto per la prima volta nel 1887 da Schmidt. In questo articolo viene illustrato il caso di una donna di 56 anni ricoverata con diagnosi di angiosarcoma della mammella destra insorta successivamente a trattamento chirurgico conservativo (BCT) con procedura del nodo sentinella (SNB) e trattamento radioterapico adiuvante 5 anni prima. La paziente p stata trattata con mastectomia semplice e dimessa dall’ospedale due giorni dopo.

Publication types

  • Case Reports

MeSH terms

  • Breast Neoplasms / radiotherapy*
  • Breast Neoplasms / surgery
  • Carcinoma / radiotherapy*
  • Carcinoma / surgery
  • Combined Modality Therapy
  • Female
  • Hemangiosarcoma / diagnosis
  • Hemangiosarcoma / etiology*
  • Hemangiosarcoma / surgery
  • Humans
  • Mastectomy, Segmental
  • Mastectomy, Simple
  • Middle Aged
  • Neoplasms, Radiation-Induced / diagnosis
  • Neoplasms, Radiation-Induced / etiology*
  • Neoplasms, Radiation-Induced / surgery
  • Neoplasms, Second Primary / diagnosis
  • Neoplasms, Second Primary / etiology*
  • Neoplasms, Second Primary / surgery
  • Prognosis
  • Radiotherapy, Adjuvant / adverse effects*
  • Sentinel Lymph Node Biopsy
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / etiology*
  • Skin Neoplasms / surgery