Abstract
The presentation of anaplastic lymphoma kinase protein (ALK)-negative anaplastic large cell lymphoma (ALCL) in bone is rare. We describe a patient with ALK-negative ALCL presenting with clinical and radiographic findings suggesting osteomyelitis 6 months after left rotator cuff repair surgery. A review of the characteristics of ALK-negative ALCL with primary bone involvement is presented. ALCL should be considered in patients not responding to therapies for osteomyelitis.
2016 BMJ Publishing Group Ltd.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Bone Neoplasms / diagnosis*
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Bone Neoplasms / drug therapy
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Cyclophosphamide / therapeutic use
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Diagnosis, Differential
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Doxorubicin / therapeutic use
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Etoposide / therapeutic use
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Humans
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Lymphatic Metastasis
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Lymphoma, Large-Cell, Anaplastic / diagnosis*
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Lymphoma, Large-Cell, Anaplastic / drug therapy
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Multimodal Imaging
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Osteomyelitis / diagnosis*
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Positron Emission Tomography Computed Tomography
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Prednisone / therapeutic use
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Shoulder
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Skin Neoplasms / secondary
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Vincristine / therapeutic use
Substances
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Vincristine
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Etoposide
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Doxorubicin
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Cyclophosphamide
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Prednisone