Increased Antiviral Treatment Among Hospitalized Children and Adults With Laboratory-Confirmed Influenza, 2010-2015

Grace D Appiah; Sandra S Chaves; Pam D Kirley; Lisa Miller; James Meek; Evan Anderson; Oluwakemi Oni; Patricia Ryan; Seth Eckel; Ruth Lynfield; Marisa Bargsten; Shelley M Zansky; Nancy Bennett; Krista Lung; Christie McDonald-Hamm; Ann Thomas; Diane Brady; Mary L Lindegren; William Schaffner; Mary Hill; Shikha Garg; Alicia M Fry; Angela P Campbell

doi:10.1093/cid/ciw745

Increased Antiviral Treatment Among Hospitalized Children and Adults With Laboratory-Confirmed Influenza, 2010-2015

Clin Infect Dis. 2017 Feb 1;64(3):364-367. doi: 10.1093/cid/ciw745. Epub 2016 Nov 10.

Authors

Grace D Appiah^{1

2}, Sandra S Chaves³, Pam D Kirley², Lisa Miller⁴, James Meek⁵, Evan Anderson⁶, Oluwakemi Oni⁷, Patricia Ryan⁸, Seth Eckel⁹, Ruth Lynfield¹⁰, Marisa Bargsten¹¹, Shelley M Zansky¹², Nancy Bennett³, Krista Lung¹³, Christie McDonald-Hamm¹⁴, Ann Thomas¹⁵, Diane Brady¹⁶, Mary L Lindegren¹⁷, William Schaffner¹⁷, Mary Hill¹⁸, Shikha Garg³, Alicia M Fry³, Angela P Campbell¹⁹

Affiliations

¹ Epidemic Intelligence Service and Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia; ydg3@cdc.gov.
² California Emerging Infections Program, Oakland.
³ Epidemic Intelligence Service and Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia.
⁴ Colorado Department of Public Health and Environment, Denver.
⁵ Connecticut Emerging Infections Program, Yale School of Public Health, New Haven.
⁶ Departments of Pediatrics and Medicine, Emory University School of Medicine, and Atlanta Veterans Affairs Medical Center, Atlanta, Georgia.
⁷ Iowa Department of Health, Des Moines.
⁸ Maryland Department of Health and Mental Hygiene, Baltimore.
⁹ Michigan Department of Health and Human Services, Lansing.
¹⁰ Minnesota Department of Health, St Paul.
¹¹ New Mexico Department of Health, Santa Fe.
¹² New York State Department of Health, Albany; University of Rochester School of Medicine and Dentistry, Rochester, New York.
¹³ Ohio Department of Health, Columbus.
¹⁴ Oklahoma Department of Health, Oklahoma City.
¹⁵ Oregon Department of Public Health, Portland.
¹⁶ Rhode Island Department of Health, Providence.
¹⁷ Vanderbilt University School of Medicine, Nashville, Tennessee; and.
¹⁸ Utah Department of Health, Salt Lake City.
¹⁹ Epidemic Intelligence Service and Influenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia; ydg3@cdc.gov app4@cdc.gov.

Abstract

(See the Editorial Commentary by Martin on pages 368-9.)Using population-based surveillance data, we analyzed antiviral treatment among hospitalized patients with laboratory-confirmed influenza. Treatment increased after the influenza A(H1N1) 2009 pandemic from 72% in 2010-2011 to 89% in 2014-2015 (P < .001). Overall, treatment was higher in adults (86%) than in children (72%); only 56% of cases received antivirals on the day of admission.

Keywords: antiviral; influenza; oseltamivir..

MeSH terms

Adolescent
Adult
Aged
Antiviral Agents / therapeutic use*
Child
Child, Preschool
Cohort Studies
Female
Humans
Infant
Infant, Newborn
Influenza A Virus, H1N1 Subtype*
Influenza, Human / drug therapy*
Influenza, Human / epidemiology*
Length of Stay
Longitudinal Studies
Male
Middle Aged
Oseltamivir / therapeutic use*
Pandemics
Prospective Studies
Retrospective Studies
Seasons
United States / epidemiology
Young Adult

Substances

Antiviral Agents
Oseltamivir

Abstract

MeSH terms

Substances

Grants and funding