Leakage of pancreaticojejunostomy basically determines the morbidity and mortality of pancreatic head resection. Aggressive pancreatic juice affects the integrity of the anastomosis and the occurrence of local pancreatitis is increased due to manipulation of the pancreas during creation of the anastomosis. A multitude of anastomotic techniques have been developed aimed at minimizing the leakage rate of up to 20%. Ideal would be a simple technique that can be carried out independently of the softness of the pancreas and the diameter of the pancreatic duct. We present three anastomotic techniques: the classical duct-to-mucosa pancreaticojejunostomy (Cattell-Warren anastomosis), the invagination pancreaticojejunostomy and the Blumgart anastomosis. Based on the available literature, the advantages and disadvantages of each technique are explained. The Blumgart anastomosis and the invagination pancreaticojejunostomy seem to be superior to the Cattell-Warren anastomosis; however, the available data cannot be directly compared. Currently, a prospective randomized study is being conducted to evaluate the importance of the Blumgart anastomosis.
Keywords: Anastomotic leakage; Morbidity; Pancreaticoduodenectomy; Pancreatitis; Surgical anastomosis.