Abstract
Prostate-specific membrane antigen (PSMA) can serve as a molecular cell surface target for the detection and treatment of prostate cancer. Near-infrared (NIR) fluorescence imaging enables highly sensitive, rapid, and non-radioactive imaging of PSMA, though specific targeting still remains a challenge because no optimized contrast agents exist.
MeSH terms
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Animals
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Antigens, Surface / analysis*
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Contrast Media / analysis*
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Contrast Media / chemistry
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Glutamate Carboxypeptidase II / analysis*
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Humans
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Male
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Mice
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Molecular Structure
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Neoplasms, Experimental / diagnostic imaging
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Optical Imaging*
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Prostatic Neoplasms / diagnostic imaging*
Substances
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Antigens, Surface
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Contrast Media
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FOLH1 protein, human
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Glutamate Carboxypeptidase II