Choroidal Neovascularization in Malattia Leventinese Diagnosed Using Optical Coherence Tomography Angiography

Am J Ophthalmol. 2017 Apr:176:108-117. doi: 10.1016/j.ajo.2016.12.027. Epub 2017 Jan 11.

Abstract

Purpose: To compare optical coherence tomography angiography (OCT-A) with traditional multimodal imaging in patients with Malattia Leventinese.

Design: Retrospective case series.

Methods: Eight eyes of 4 consecutive patients with Malattia Leventinese were retrospectively studied. All patients underwent a complete ophthalmologic examination including color fundus photography, fluorescein and indocyanine green angiographies, spectral-domain optical coherence tomography, and optical coherence tomography angiography.

Results: The choriocapillaris segmentation of OCT-A revealed the presence of a hyperflow signal corresponding to active choroidal neovascularization in 3 eyes and inactive choroidal neovascularization in 1 eye. Traditional multimodal imaging did not show each vascular layer and any leakage in these cases.

Conclusion: OCT-A, unlike traditional multimodal imaging, helps diagnose choroidal neovascularization in patients with Malattia Leventinese suffering from metamorphopsia and reduced visual acuity.

Publication types

  • Comparative Study

MeSH terms

  • Choroid / diagnostic imaging*
  • Choroidal Neovascularization / diagnosis*
  • Choroidal Neovascularization / etiology
  • Female
  • Fluorescein Angiography / methods*
  • Fundus Oculi
  • Humans
  • Male
  • Middle Aged
  • Optic Disk Drusen / complications
  • Optic Disk Drusen / congenital
  • Optic Disk Drusen / diagnosis
  • Reproducibility of Results
  • Retina / diagnostic imaging*
  • Retrospective Studies
  • Tomography, Optical Coherence / methods*
  • Visual Acuity

Supplementary concepts

  • Doyne honeycomb retinal dystrophy