Long Noncoding RNAs in Pathological Cardiac Remodeling

Janika Viereck; Thomas Thum

doi:10.1161/CIRCRESAHA.116.310174

Long Noncoding RNAs in Pathological Cardiac Remodeling

Circ Res. 2017 Jan 20;120(2):262-264. doi: 10.1161/CIRCRESAHA.116.310174.

Authors

Janika Viereck¹, Thomas Thum²

Affiliations

¹ From the Institute of Molecular and Translational Therapeutic Strategies, IFB-Tx (J.V., T.T.) and Excellence Cluster REBIRTH (T.T.), Hannover Medical School, Germany; and National Heart and Lung Institute, Imperial College London, United Kingdom (T.T.).
² From the Institute of Molecular and Translational Therapeutic Strategies, IFB-Tx (J.V., T.T.) and Excellence Cluster REBIRTH (T.T.), Hannover Medical School, Germany; and National Heart and Lung Institute, Imperial College London, United Kingdom (T.T.). thum.thomas@mh-hannover.de.

PMID: 28104764
DOI: 10.1161/CIRCRESAHA.116.310174

Abstract

A novel long noncoding RNA Chaer acts as noncoding epigenetic regulator at the onset of cardiac hypertrophy and enables an improved understanding about the complex mechanisms in cardiovascular disease.

Publication types

Review

MeSH terms

Animals
Cardiomegaly / diagnosis
Cardiomegaly / genetics
Cardiomegaly / physiopathology
Cardiovascular Diseases / diagnosis
Cardiovascular Diseases / genetics*
Cardiovascular Diseases / physiopathology
Humans
RNA, Long Noncoding / genetics*
Ventricular Remodeling / genetics*

Substances

RNA, Long Noncoding