Dimethyl fumarate accelerates peripheral nerve regeneration via activation of the anti-inflammatory and cytoprotective Nrf2/HO-1 signaling pathway

MeSH terms

• Animals
• Anti-Inflammatory Agents / pharmacology*
• Dimethyl Fumarate / pharmacology*
• Disease Models, Animal
• Heme Oxygenase-1 / metabolism*
• Malondialdehyde / metabolism
• Membrane Proteins / metabolism*
• Mice, Inbred C57BL
• Muscle Strength / drug effects
• Muscle Strength / physiology
• NF-E2-Related Factor 2 / metabolism*
• Nerve Regeneration / drug effects*
• Nerve Regeneration / physiology
• Neuroprotective Agents / pharmacology*
• Recovery of Function / drug effects
• Recovery of Function / physiology
• Sciatic Nerve / drug effects
• Sciatic Nerve / injuries
• Sciatic Nerve / metabolism
• Sciatic Nerve / pathology
• Signal Transduction / drug effects