Deletion of Ptpn1 induces myeloproliferative neoplasm

Leukemia. 2017 May;31(5):1229-1234. doi: 10.1038/leu.2017.31. Epub 2017 Jan 23.

Authors

F Jobe¹, B Patel², T Kuzmanovic², H Makishima², Y Yang¹, B Przychodzen², R E Hutchison³, K K Bence⁴, J P Maciejewski², G Mohi¹

Affiliations

¹ Department of Pharmacology, SUNY Upstate Medical University, Syracuse, NY, USA.
² Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH, USA.
³ Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, USA.
⁴ Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, USA.

No abstract available

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Chromosomes, Human, Pair 20
Cohort Studies
Flow Cytometry
Gene Deletion*
Hematologic Neoplasms / genetics*
Humans
In Situ Hybridization, Fluorescence
Mice
Mice, Knockout
Myeloproliferative Disorders / genetics*
Protein Tyrosine Phosphatase, Non-Receptor Type 1 / genetics*

Substances

PTPN1 protein, human
Protein Tyrosine Phosphatase, Non-Receptor Type 1

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