Codon Clarity or Conundrum?

Daniel P Aalberts; Gregory Boël; John F Hunt

doi:10.1016/j.cels.2017.01.004

Codon Clarity or Conundrum?

Cell Syst. 2017 Jan 25;4(1):16-19. doi: 10.1016/j.cels.2017.01.004.

Authors

Daniel P Aalberts¹, Gregory Boël², John F Hunt³

Affiliations

¹ Physics Department, Williams College, Williamstown, MA 01267, USA. Electronic address: aalberts@williams.edu.
² Institut de Biologie Physico-Chemique, CNRS, 75005 Paris, France. Electronic address: boel@ibpc.fr.
³ Department of Biological Sciences, Columbia University, New York, NY 10024, USA. Electronic address: jfh21@columbia.edu.

Abstract

Synonymous variations in protein-coding sequences alter protein expression dynamics, which has important implications for cellular physiology and evolutionary fitness, but disentangling the underlying molecular mechanisms remains challenging.

Publication types

Comment

MeSH terms

Biological Evolution*
Codon
Gene Expression
Open Reading Frames

Substances

Codon

Abstract

Publication types

MeSH terms

Substances

Grants and funding