Combined effectiveness of prior and current season influenza vaccination in northern Spain: 2016/17 mid-season analysis

Euro Surveill. 2017 Feb 16;22(7):30465. doi: 10.2807/1560-7917.ES.2017.22.7.30465.

Abstract

The 2016/17 mid-season vaccine effectiveness estimate against influenza A(H3N2) was 15% (95% confidence interval: -11 to 35) in Navarre. Comparing to individuals unvaccinated in the current and four prior seasons, effectiveness was 24% for current and 3-4 prior doses, 61% for current and 1-2 prior doses, 42% for only current vaccination, and 58% for 3-4 prior doses. This suggests moderate effectiveness for different combinations of vaccination in the current and prior seasons.

Keywords: case control study; influenza; influenza vaccine; influenza-like illness; repeated vaccination; vaccine effectiveness.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Case-Control Studies
  • Child
  • Female
  • Humans
  • Influenza A Virus, H3N2 Subtype / immunology*
  • Influenza Vaccines / immunology
  • Influenza Vaccines / therapeutic use*
  • Influenza, Human / epidemiology
  • Influenza, Human / prevention & control*
  • Male
  • Middle Aged
  • Rural Population
  • Seasons*
  • Sentinel Surveillance
  • Spain / epidemiology
  • Urban Population
  • Vaccination / statistics & numerical data*
  • Young Adult

Substances

  • Influenza Vaccines