Management of Prosthetic Joint Infection

Infect Dis Clin North Am. 2017 Jun;31(2):237-252. doi: 10.1016/j.idc.2017.01.009. Epub 2017 Mar 30.

Abstract

Although uncommon, prosthetic joint infection is a devastating complication. This challenging condition requires a coordinated management approach to achieve good patient outcomes. This review details the general principles to consider when managing patients with prosthetic joint infection. The different medical/surgical treatment strategies and how to appropriately select a strategy are discussed. The data to support each strategy are presented, along with discussion of antimicrobial strategies in specific situations.

Keywords: 2-Stage exchange; Joint arthroplasty; Joint replacement; Osteomyelitis; Periprosthetic joint infection; Prosthetic joint infection; Septic arthritis.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Infectious / diagnosis
  • Arthritis, Infectious / drug therapy
  • Arthroplasty, Replacement / adverse effects
  • Debridement
  • Disease Management
  • Humans
  • Infection Control / methods*
  • Joint Prosthesis / adverse effects*
  • Osteomyelitis / drug therapy
  • Osteomyelitis / microbiology
  • Prosthesis-Related Infections / drug therapy
  • Prosthesis-Related Infections / microbiology
  • Prosthesis-Related Infections / surgery
  • Prosthesis-Related Infections / therapy*

Substances

  • Anti-Bacterial Agents