Fertility after surgery for deep infiltrating endometriosis

J Gynecol Obstet Hum Reprod. 2017 Feb;46(2):143-146. doi: 10.1016/j.jogoh.2016.12.005. Epub 2017 Jan 30.

Abstract

Objectives: The population of Reunion Island has a high prevalence of endometriosis impacting fertility. The aim of this series is to assess the fertility of women undergoing surgical approach of deep infiltrating endometriosis and to study the characteristics of the pregnancy outcomes.

Material and methods: This is a retrospective 2 centers study, including all women wanting to be pregnant and operated for deep endometriosis in any of the 2 hospitals of the CHU of Reunion Island between January 2012 and May 2013.

Results: Sixty-three women were included. Twenty-four (38%) had more than one operation and 16 (25.4%) experienced one or more complications. Fifty-eight (92%) had complete resection of the endometriosis. Twenty-seven (42.9%) women became pregnant at least once, spontaneously in 44.4%. Average delay for first pregnancy was 14.2 months. Twenty-two (34.9%) women became pregnant before 24 months. Among the 34 pregnancies, 20 ended with a live newborn. Premature delivery rate was 35%, cesarean section rate 10% and average birth weight was at 45th percentile.

Conclusion: Fertility remains good after surgery for deep infiltrating endometriosis but the delay between operation and pregnancy is increased when a surgical complication occurs. Premature delivery rate is high. No pregnancy occurred in case of incomplete resection or after age of 36.

Keywords: Deep infiltrating endometriosis; Fertility.

Publication types

  • Multicenter Study

MeSH terms

  • Adult
  • Endometriosis / complications
  • Endometriosis / epidemiology
  • Endometriosis / surgery*
  • Female
  • Fertility / physiology*
  • Gynecologic Surgical Procedures / methods
  • Gynecologic Surgical Procedures / rehabilitation
  • Gynecologic Surgical Procedures / statistics & numerical data
  • Humans
  • Infertility, Female / epidemiology
  • Infertility, Female / etiology
  • Infertility, Female / surgery*
  • Laparoscopy / methods
  • Laparoscopy / rehabilitation
  • Laparoscopy / statistics & numerical data
  • Peritoneal Diseases / complications
  • Peritoneal Diseases / epidemiology
  • Peritoneal Diseases / surgery*
  • Pregnancy
  • Pregnancy Outcome / epidemiology*
  • Pregnancy Rate
  • Retrospective Studies
  • Reunion / epidemiology
  • Young Adult