Discrimination between different groups of Candida parapsilosis by mitochondrial DNA restriction analysis

Curr Genet. 1988 May;13(5):445-9. doi: 10.1007/BF00365667.

Abstract

The analysis of mitochondrial DNA (mtDNA) from several strains of Candida parapsilosis and Candida rhagii by restriction endonucleases enabled us to discriminate between several groups within the C. parapsilosis species and to allocate laboratory strains to one of these. The mtDNAs isolated ranged in size from 20 to 31 kb. The mtDNA isolated from group 1 C. parapsilosis hybridises with both ATPase subunit 6 and 8 gene probes, the same restriction fragment hybridising with both probes.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Candida / genetics*
  • DNA Restriction Enzymes
  • DNA, Mitochondrial / genetics*
  • Genes, Fungal*
  • Nucleic Acid Hybridization
  • Nucleotide Mapping
  • Species Specificity

Substances

  • DNA, Mitochondrial
  • DNA Restriction Enzymes