Myocardial Infarction Following Intravenous Thrombolysis for Acute Ischemic Stroke: Case Report and Literature Review

J Stroke Cerebrovasc Dis. 2017 Jun;26(6):e105-e107. doi: 10.1016/j.jstrokecerebrovasdis.2017.02.039. Epub 2017 Apr 20.

Abstract

Embolic complications of intravenous thrombolysis for acute ischemic stroke are increasingly recognized, and to date several cases of myocardial infarction soon after the administration of alteplase have been reported. We describe a case of early anterior myocardial infarction during intravenous thrombolysis for stroke and review the current literature.

Keywords: Acute ischemic stroke; intravenous thrombolysis; myocardial infarction; t-PA.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anterior Wall Myocardial Infarction / chemically induced*
  • Anterior Wall Myocardial Infarction / diagnostic imaging
  • Anterior Wall Myocardial Infarction / therapy
  • Brain Ischemia / diagnostic imaging
  • Brain Ischemia / drug therapy*
  • Embolism / chemically induced*
  • Embolism / diagnostic imaging
  • Embolism / therapy
  • Fatal Outcome
  • Female
  • Fibrinolytic Agents / administration & dosage
  • Fibrinolytic Agents / adverse effects*
  • Humans
  • Infusions, Intravenous
  • Stroke / diagnostic imaging
  • Stroke / drug therapy*
  • Thrombolytic Therapy / adverse effects*
  • Tissue Plasminogen Activator / administration & dosage
  • Tissue Plasminogen Activator / adverse effects*

Substances

  • Fibrinolytic Agents
  • Tissue Plasminogen Activator