Metastatic pleomorphic liposarcoma in the mediastinum is rare, and the current treatments are most of the times ineffective. We hereby report a case with relapsed pleomorphic liposarcoma adjacent to the psoas major muscle and with mediastinal metastasis, to discuss the clinical features and treatment strategies of pleomorphic liposarcoma. The patient's clinical history, imaging findings, pathological diagnosis, and multidisciplinary treatments were retrospectively analyzed. A 41-year old female patient was diagnosed with pleomorphic liposarcoma adjacent to the psoas major muscle and mediastinal metastasis. After multidisciplinary treatments, including surgery, chemotherapy, and targeted therapy, the patient has survived 65 months until now. Surgical resection is considered as the first choice of the treatment for pleomorphic liposarcoma. Multidisciplinary treatments, including chemotherapy and other medical treatments, are effective to slow the disease progression and to reduce the disease recurrence.
纵隔内转移性多形性脂肪肉瘤为纵隔内肿瘤的罕见病种，目前总体治疗效果欠佳。本文介绍腰大肌旁多形性脂肪肉瘤复发伴纵隔转移1例，探讨多形性脂肪肉瘤的临床特点和治疗策略。回顾性分析我院收治的1例转移性多形性脂肪肉瘤患者，基于影像学诊断与手术病理诊断，对患者进行针对性的多学科综合治疗。一名41岁女性患者，诊断腰大肌旁多形性脂肪肉瘤伴纵隔转移。经手术、靶向及化疗等多学科治疗，随访至今已65个月。对于多形性脂肪肉瘤治疗策略，应以外科完整切除为首选，术后辅助相关内科治疗，多学科综合治疗以延缓患者病情进展及复发。.