Low prevalence search for cancers in mammograms: Evidence using laboratory experiments and computer aided detection

J Exp Psychol Appl. 2017 Dec;23(4):369-385. doi: 10.1037/xap0000132. Epub 2017 May 25.

Abstract

People miss a large proportion of targets when they only appear rarely. This Low Prevalence (LP) Effect could lead to serious consequences if it occurred in the real-world task of searching for cancers in mammograms. Using a novel mammogram search task, we asked participants to search for a prespecified cancer (Experiments 1-2) or a range of masses (Experiments 3-5) under high or low prevalence conditions. Experiment 1 showed that an LP Effect occurred using these stimuli. Experiment 2 tested an overreliance hypothesis and showed that the use of Computer Aided Detection (CAD) led to fewer missed cancers with a valid CAD prompt yet, a large proportion of cancers were missed when CAD was incorrect. Experiment 3-5 showed that false alarms also increased when searching for a range of masses and that CAD reduced miss errors when it correctly cued the target but increased miss errors and false alarms when it did not. Furthermore, when a mass fell outside the CAD prompt it was more likely to be misidentified. No LP Effect was observed with the addition of CAD when people were asked to search for a range of targets. Theories and implications for mammogram search are discussed. (PsycINFO Database Record

MeSH terms

  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / epidemiology*
  • Diagnostic Errors / statistics & numerical data*
  • Female
  • Humans
  • Male
  • Mammography / methods*
  • Observer Variation
  • Prevalence
  • Radiographic Image Interpretation, Computer-Assisted / methods*
  • Young Adult