Interleukin-6 G-174C polymorphism predicts higher risk of stroke in sickle cell anaemia

Br J Haematol. 2018 Jul;182(2):294-297. doi: 10.1111/bjh.14773. Epub 2017 May 23.

Affiliations

¹ Department of Genetics, Federal University of Pernambuco, Recife, Brazil.
² Department of Internal Medicine, Haematology and Haemotherapy Foundation of Pernambuco, Recife, Brazil.
³ Haematology and Haemotherapy Centre, University of Campinas, São Paulo, Brazil.
⁴ Department of Medical Sciences, University of Pernambuco, Recife, Brazil.

PMID: 28542795
DOI: 10.1111/bjh.14773

No abstract available

Keywords: IL6 G-174C polymorphism; IL6 genotype; cerebrovascular disease; sickle cell anaemia; transcranial Doppler.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Adult
Anemia, Sickle Cell / genetics*
Child
Child, Preschool
Female
Genotype
Humans
Interleukin-6 / genetics*
Male
Polymorphism, Single Nucleotide / genetics*
Risk Factors
Stroke / genetics*
Young Adult

Substances

IL6 protein, human
Interleukin-6