The changing epidemiology and demography of cystic fibrosis

Anne L Stephenson; Sanja Stanojevic; Jenna Sykes; Pierre-Regis Burgel

doi:10.1016/j.lpm.2017.04.012

The changing epidemiology and demography of cystic fibrosis

Presse Med. 2017 Jun;46(6 Pt 2):e87-e95. doi: 10.1016/j.lpm.2017.04.012. Epub 2017 May 26.

Authors

Anne L Stephenson¹, Sanja Stanojevic², Jenna Sykes³, Pierre-Regis Burgel⁴

Affiliations

¹ University of Toronto, St-Michael's hospital, Li Ka Shing knowledge institute, Keenan research centre, department of medicine, adult CF program, 30, Bond street, 6th floor, Bond Wing, M5B 1W8 Toronto, ON, Canada; University of Toronto, institute of health policy, management and evaluation, Toronto, ON, Canada. Electronic address: stephensona@smh.ca.
² The hospital for sick children, division of respiratory medicine, Toronto, ON, Canada; University of Toronto, institute of health policy, management and evaluation, Toronto, ON, Canada.
³ University of Toronto, St-Michael's hospital, Li Ka Shing knowledge institute, Keenan research centre, department of medicine, adult CF program, 30, Bond street, 6th floor, Bond Wing, M5B 1W8 Toronto, ON, Canada.
⁴ Sorbonne Paris Cité, université Paris Descartes, 75014 Paris, France; Assistance publique-Hôpitaux de Paris, hôpital Cochin, 75014 Paris, France.

PMID: 28554720
DOI: 10.1016/j.lpm.2017.04.012

Abstract

Once considered a pediatric disease with a poor prognosis, individuals born with cystic fibrosis (CF) today can expect to live well into adulthood. The implementation of multidisciplinary care, novel treatments and newborn screening has resulted in the rapid evolution in the demographics of the CF population. The purpose of this review is to highlight the evolving epidemiology and demographics of the CF population internationally.

Publication types

Comparative Study

MeSH terms

Adolescent
Adult
Canada
Child
Child, Preschool
Cross-Cultural Comparison
Cross-Sectional Studies
Cystic Fibrosis / epidemiology*
Cystic Fibrosis / mortality
Cystic Fibrosis / therapy
Demography*
Europe
Humans
Infant
Infant, Newborn
Interdisciplinary Communication
Intersectoral Collaboration
Life Expectancy*
Neonatal Screening
Registries
United States
Young Adult