Three-Dimensional Power Doppler Vascularization in Women With Ovarian Endometriomas and Relationship With Associated Painful Symptoms

J Ultrasound Med. 2017 Nov;36(11):2271-2278. doi: 10.1002/jum.14258. Epub 2017 May 27.

Abstract

Objectives: The objective of the study was to evaluate the correlation between endometrioma-associated pain and lesion vascularization as measured with 3-dimensional power Doppler transvaginal sonography.

Methods: Endometriomas were examined, and 4 indices were obtained: mean grayness, flow index, vascularization index, and vascularization-flow index. Dysmenorrhea, chronic pelvic pain, and dyspareunia were analyzed in terms of severity, presence/absence, and duration.

Results: Twenty-nine women were selected. The univariable association of painful symptoms in terms of presence/absence and duration was low with the exception of mean grayness with the presence of chronic pelvic pain (β = -0.106; P = .047; 95% confidence interval, 0.810 to 0.998). The R2 value increased to 0.226 for dysmenorrhea (β = -0.475; P = .029) when analyzing the association between the vascularization index and the severity of painful symptoms. The visual analog scale scores for chronic pelvic pain and dyspareunia were higher (R2 = 0.300; β = -0.547 and -0.548, respectively; P = .028 and .053).

Conclusions: We observed an inverse association between the severity of pain and endometrioma vascularization. Further larger studies are required to confirm our findings.

Keywords: 3-dimensional sonography; chronic pelvic pain; dysmenorrhea; dyspareunia; endometriosis; gynecologic ultrasound.

MeSH terms

  • Adult
  • Endometriosis / complications*
  • Endometriosis / diagnostic imaging*
  • Female
  • Humans
  • Imaging, Three-Dimensional / methods*
  • Ovarian Diseases / complications
  • Ovarian Diseases / diagnostic imaging*
  • Ovary / diagnostic imaging
  • Pelvic Pain / etiology*
  • Prospective Studies
  • Severity of Illness Index
  • Ultrasonography, Doppler / methods*