Sentinel lymph node mapping and staging in endometrial cancer: A Society of Gynecologic Oncology literature review with consensus recommendations

Gynecol Oncol. 2017 Aug;146(2):405-415. doi: 10.1016/j.ygyno.2017.05.027. Epub 2017 May 28.

Abstract

The emphasis in contemporary medical oncology has been "precision" or "personalized" medicine, terms that imply a strategy to improve efficacy through targeted therapies. Similar attempts at precision are occurring in surgical oncology. Sentinel lymph node (SLN) mapping has recently been introduced into the surgical staging of endometrial cancer with the goal to reduce morbidity associated with comprehensive lymphadenectomy, yet obtain prognostic information from lymph node status. The Society of Gynecologic Oncology's (SGO) Clinical Practice Committee and SLN Working Group reviewed the current literature for preparation of this document. Literature-based recommendations for the inclusion of SLN assessment in the treatment of patients with endometrial cancer are presented. This article examines.

Keywords: Consensus recommendation; Endometrial cancer; Literature review; Pathology & clinical outcomes; Sentinel lymph node mapping; Surgical staging.

Publication types

  • Consensus Development Conference
  • Review

MeSH terms

  • Adenocarcinoma, Clear Cell / pathology*
  • Adenocarcinoma, Clear Cell / surgery
  • Carcinoma, Endometrioid / pathology*
  • Carcinoma, Endometrioid / surgery
  • Carcinosarcoma / pathology*
  • Carcinosarcoma / surgery
  • Colorimetry
  • Coloring Agents
  • Endometrial Neoplasms / pathology*
  • Endometrial Neoplasms / surgery
  • Female
  • Gynecology
  • Humans
  • Indocyanine Green
  • Lymph Node Excision
  • Neoplasm Staging
  • Neoplasms, Cystic, Mucinous, and Serous / pathology*
  • Neoplasms, Cystic, Mucinous, and Serous / surgery
  • Organotechnetium Compounds
  • Sentinel Lymph Node / pathology*
  • Sentinel Lymph Node Biopsy / methods*
  • Single Photon Emission Computed Tomography Computed Tomography
  • Societies, Medical
  • Spectroscopy, Near-Infrared
  • Surgical Oncology

Substances

  • Coloring Agents
  • Organotechnetium Compounds
  • Indocyanine Green