Clozapine in Reducing Aggression and Violence in Forensic Populations

Psychiatr Q. 2018 Mar;89(1):157-168. doi: 10.1007/s11126-017-9521-z.

Abstract

Popular media often portray people with a mental illness as being aggressive, violent, and incarcerated as a result of their behavior. Despite exaggeration in the media, risks for some aggressive behaviors are in fact higher in individuals with schizophrenia. This is often the case with influence of comorbid substance use disorders. It is essential that mental health professionals are aware of treatments that may help with attenuating and treating behaviors that contribute to violence, aggression and incarceration. This paper reviews violence and incarceration in individuals with schizophrenia as well as recommendations, guidelines and benefits for the use of clozapine in this population. Clozapine remains one of the most underutilized evidence-based medications available in the psychiatric arena in the United States. It is a viable and recommended option in the forensic population and it may be helpful on the path to recovery as well as bring substantial savings to the criminal justice system.

Keywords: Aggression; Clozapine; Criminal justice; Forensic; Violence.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aggression / drug effects*
  • Antipsychotic Agents / therapeutic use*
  • Clozapine / therapeutic use*
  • Criminal Law*
  • Criminals*
  • Humans
  • Schizophrenia / drug therapy*
  • Violence / prevention & control*

Substances

  • Antipsychotic Agents
  • Clozapine