Genetic Diversity of Highly Pathogenic Avian Influenza A(H5N8/H5N5) Viruses in Italy, 2016-17

Emerg Infect Dis. 2017 Sep;23(9):1543-1547. doi: 10.3201/eid2309.170539. Epub 2017 Sep 17.

Abstract

In winter 2016-17, highly pathogenic avian influenza A(H5N8) and A(H5N5) viruses of clade 2.3.4.4 were identified in wild and domestic birds in Italy. We report the occurrence of multiple introductions and describe the identification in Europe of 2 novel genotypes, generated through multiple reassortment events.

Keywords: H5N5 subtype; H5N8 subtype; Italy; highly pathogenic avian influenza; influenza; influenza A virus; phylogeny; reassortments; respiratory infections; viruses; zoonoses.

MeSH terms

  • Animals
  • Animals, Wild / virology
  • Birds / virology
  • Genetic Variation*
  • Genotype
  • Influenza A Virus, H5N8 Subtype / genetics
  • Influenza A Virus, H5N8 Subtype / pathogenicity
  • Influenza A virus / classification
  • Influenza A virus / genetics*
  • Influenza A virus / pathogenicity*
  • Influenza in Birds / virology*
  • Italy
  • Phylogeny
  • Reassortant Viruses / genetics
  • Reassortant Viruses / pathogenicity
  • Turkeys