Method for temporal keyhole lobectomies in resection of low- and high-grade gliomas

J Neurosurg. 2018 May;128(5):1388-1395. doi: 10.3171/2016.12.JNS162168. Epub 2017 Jul 7.

Abstract

OBJECTIVE The purpose of this study was to describe a method of resecting temporal gliomas through a keyhole lobectomy and to share the results of using this technique. METHODS The authors performed a retrospective review of data obtained in all patients in whom the senior author performed resection of temporal gliomas between 2012 and 2015. The authors describe their technique for resecting dominant and nondominant gliomas, using both awake and asleep keyhole craniotomy techniques. RESULTS Fifty-two patients were included in the study. Twenty-six patients (50%) had not received prior surgery. Seventeen patients (33%) were diagnosed with WHO Grade II/III tumors, and 35 patients (67%) were diagnosed with a glioblastoma. Thirty tumors were left sided (58%). Thirty procedures (58%) were performed while the patient was awake. The median extent of resection was 95%, and at least 90% of the tumor was resected in 35 cases (67%). Five of 49 patients (10%) with clinical follow-up experienced permanent deficits, including 3 patients (6%) with hydrocephalus requiring placement of a ventriculoperitoneal shunt and 2 patients (4%) with weakness. Three patients experienced early postoperative anomia, but no patients had a new speech deficit at clinical follow-up. CONCLUSIONS The authors provide their experience using a keyhole lobectomy for resecting temporal gliomas. Their data demonstrate the feasibility of using less invasive techniques to safely and aggressively treat these tumors.

Keywords: DTI = diffusion tensor imaging; EOR = extent of resection; IFOF = inferior frontooccipital fasciculus; POD = postoperative day; SLF = superior longitudinal fasciculus; STG = superior temporal gyrus; craniotomy; glioma; keyhole; minimally invasive; oncology; resection; temporal lobe.

Publication types

  • Video-Audio Media

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Brain Neoplasms / diagnostic imaging
  • Brain Neoplasms / pathology
  • Brain Neoplasms / surgery*
  • Craniotomy / methods
  • Feasibility Studies
  • Female
  • Follow-Up Studies
  • Glioma / diagnostic imaging
  • Glioma / pathology
  • Glioma / surgery*
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Grading
  • Neurosurgical Procedures / methods*
  • Retrospective Studies
  • Surgery, Computer-Assisted
  • Temporal Lobe / diagnostic imaging
  • Temporal Lobe / pathology
  • Temporal Lobe / surgery*
  • Treatment Outcome
  • Wakefulness
  • Young Adult