Recovery from DSM-IV post-traumatic stress disorder in the WHO World Mental Health surveys

Psychol Med. 2018 Feb;48(3):437-450. doi: 10.1017/S0033291717001817. Epub 2017 Jul 19.

Abstract

Background: Research on post-traumatic stress disorder (PTSD) course finds a substantial proportion of cases remit within 6 months, a majority within 2 years, and a substantial minority persists for many years. Results are inconsistent about pre-trauma predictors.

Methods: The WHO World Mental Health surveys assessed lifetime DSM-IV PTSD presence-course after one randomly-selected trauma, allowing retrospective estimates of PTSD duration. Prior traumas, childhood adversities (CAs), and other lifetime DSM-IV mental disorders were examined as predictors using discrete-time person-month survival analysis among the 1575 respondents with lifetime PTSD.

Results: 20%, 27%, and 50% of cases recovered within 3, 6, and 24 months and 77% within 10 years (the longest duration allowing stable estimates). Time-related recall bias was found largely for recoveries after 24 months. Recovery was weakly related to most trauma types other than very low [odds-ratio (OR) 0.2-0.3] early-recovery (within 24 months) associated with purposefully injuring/torturing/killing and witnessing atrocities and very low later-recovery (25+ months) associated with being kidnapped. The significant ORs for prior traumas, CAs, and mental disorders were generally inconsistent between early- and later-recovery models. Cross-validated versions of final models nonetheless discriminated significantly between the 50% of respondents with highest and lowest predicted probabilities of both early-recovery (66-55% v. 43%) and later-recovery (75-68% v. 39%).

Conclusions: We found PTSD recovery trajectories similar to those in previous studies. The weak associations of pre-trauma factors with recovery, also consistent with previous studies, presumably are due to stronger influences of post-trauma factors.

Keywords: Cross-national; epidemiology; post-traumatic stress disorder; recovery.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Health Surveys / statistics & numerical data*
  • Humans
  • Infant
  • Infant, Newborn
  • Internationality
  • Life Change Events
  • Logistic Models
  • Male
  • Middle Aged
  • Recovery of Function*
  • Retrospective Studies
  • Stress Disorders, Post-Traumatic / rehabilitation*
  • Time Factors
  • World Health Organization
  • Wounds and Injuries / psychology*
  • Young Adult