Nanocomposites Based on PCL and Halloysite Nanotubes Filled with Lysozyme: Effect of Draw Ratio on the Physical Properties and Release Analysis

Nanomaterials (Basel). 2017 Aug 4;7(8):213. doi: 10.3390/nano7080213.

Abstract

Halloysite nanotubes (HNTs) were loaded with lsozyme, as antimicrobial molecule, at a HNTs/lysozyme ratio of 1:1. Such a nano-hybrid was incorporated into a poly (ε-caprolactone) (PCL) matrix at 10 wt % and films were obtained. The nano-composites were submitted to a cold drawn process at three different draw ratios, λ = 3, 4, and 5, where λ is l(final length)/l0(initial length). Morphology, physical, and barrier properties of the starting nanocomposite and drawn samples were studied, and correlated to the release of the lysozyme molecule. It was demonstrated that with a simple mechanical treatment it is possible to obtain controlled release systems for specific active packaging requirements.

Keywords: PCL; active packaging; controlled release; halloysite nanotubes; lysozyme.