Risk factors for measles among infants in Tianjin, China

Public Health. 2017 Oct:151:114-117. doi: 10.1016/j.puhe.2017.07.001. Epub 2017 Aug 4.

Abstract

Objectives: Infants aged <8 months are ineligible for measles vaccination in China but represent a disproportionate number of cases. We examined the risk factors for measles among infants in Tianjin, China.

Study design: Case-control study.

Methods: Cases were enrolled from a surveillance system, and IgG-negative controls were sampled from registries at immunization clinics. A logistic regression model assessed for risk factors.

Results: Among 82 cases and 485 controls, exposure to a municipal hospital (OR [odds ratio]: 5.21; 95% confidence interval [CI]: 1.19-22.82) or a specialty hospital (OR: 13.22; 95% CI: 6.13-28.51) was associated with the disease, whereas visiting a township or district hospitals was not associated with increased odds of measles.

Conclusions: Hospitals were an important focal point of measles transmission for infants. Hospitals, particularly higher-level municipal and specialty hospitals, should enforce infection control programs to separate infants with highly communicable diseases to prevent transmission.

Keywords: China; Infants; Measles.

MeSH terms

  • Case-Control Studies
  • China / epidemiology
  • Cross Infection / epidemiology
  • Female
  • Hospitals
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Measles / epidemiology*
  • Measles / transmission
  • Risk Factors