Vesicular Systems Containing Curcumin and Their Applications in Respiratory Disorders - A Mini Review

Pharm Nanotechnol. 2017;5(4):250-254. doi: 10.2174/2211738505666170808094635.

Abstract

Background: Vesicular systems like nanotechnology and liposomes are gaining tremendous attention lately in the field of respiratory diseases. These formulations enhance bioavailability of the drug candidate, which could be achieved through a novel drug delivery mechanism. Moreover, the therapeutic potential achieved through these systems is highly controllable over long durations of time providing better efficacy and patient compliance.

Objective: The objective of this paper is to review the recent literature on vesicular drug delivery systems containing curcumin.

Methods: We have collated and summarized various recent attempts made to develop different controlled release drug delivery systems containing curcumin which would be of great interest for herbal, formulation and biological scientists. There are several vesicular nanotechnological techniques involving curcumin which have been studied recently, targeting pulmonary diseases.

Results: Different vesicular systems containing curcumin are being studied for their therapeutic potential in different respiratory diseases. There has been a renewed interest in formulations containing curcumin recently, primarily owing to the broad spectrum therapeutic potential of this miracle substance. Various types of formulations, containing curcumin, targeting different bodily systems have recently emerged and, nevertheless, the search for newer frontiers with this drug goes on.

Conclusion: This mini review, in this direction, tries to highlight the key research interventions employing vesicular systems of drug delivery with curcumin.

Keywords: Curcumin; liposomes; nanotechnology; niosomes; respiratory diseases; vesicular systems.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Asthma / drug therapy
  • Asthma / physiopathology
  • Curcumin / administration & dosage
  • Curcumin / chemistry*
  • Curcumin / pharmacology
  • Delayed-Action Preparations
  • Drug Compounding / methods
  • Drug Delivery Systems / methods*
  • Humans
  • Liposomes / chemistry
  • Nanomedicine / methods
  • Nanoparticles / chemistry
  • Pulmonary Disease, Chronic Obstructive / drug therapy
  • Pulmonary Disease, Chronic Obstructive / immunology
  • Respiration Disorders / drug therapy*

Substances

  • Delayed-Action Preparations
  • Liposomes
  • Curcumin