Rescue of T-cell function during persistent pulmonary adenoviral infection by Toll-like receptor 9 activation

J Allergy Clin Immunol. 2018 Jan;141(1):416-419.e10. doi: 10.1016/j.jaci.2017.06.048. Epub 2017 Aug 19.

Authors

Tristan Holland¹, Dirk Wohlleber², Samira Marx¹, Thomas Kreutzberg¹, Salvador Vento-Asturias¹, Christine Schmitt-Mbamunyo¹, Meike Welz¹, Marianne Janas², Karl Komander¹, Sarah Eickhoff¹, Anna Brewitz¹, Mike Hasenberg³, Linda Männ³, Matthias Gunzer³, Christoph Wilhelm⁴, Wolfgang Kastenmüller¹, Percy Knolle², Zeinab Abdullah¹, Christian Kurts¹, Natalio Garbi⁵

Affiliations

¹ Institute of Experimental Immunology, University of Bonn, Bonn, Germany.
² Institute of Molecular Immunology and Experimental Oncology, Technical University Munich, Munich, Germany.
³ Institute of Experimental Immunology and Imaging, University Duisburg-Essen, Duisburg-Essen, Germany.
⁴ Institute for Clinical Chemistry and Clinical Pharmacology, University of Bonn, Bonn, Germany.
⁵ Institute of Experimental Immunology, University of Bonn, Bonn, Germany. Electronic address: ngarbi@uni-bonn.de.

PMID: 28826775
DOI: 10.1016/j.jaci.2017.06.048

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adenoviridae
Adenoviridae Infections / immunology*
Adenoviridae Infections / metabolism*
Adenoviridae Infections / virology
Animals
Biomarkers
Disease Models, Animal
Mice
Pneumonia, Viral / immunology*
Pneumonia, Viral / metabolism*
Pneumonia, Viral / virology
T-Lymphocyte Subsets / immunology
T-Lymphocyte Subsets / metabolism
T-Lymphocytes / immunology*
T-Lymphocytes / metabolism*
Toll-Like Receptor 9 / metabolism*

Substances

Biomarkers
Toll-Like Receptor 9