DOCK8 and STAT3 dependent inhibition of IgE isotype switching by TLR9 ligation in human B cells

Affiliations

• ¹ Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
• ² Department of Pediatrics, Faculty of Medicine, Kuwait University, and Allergy and Clinical Immunology Unit, Department of Pediatrics, Al-Sabah Hospital, Kuwait.
• ³ Institut de Génétique Humaine, UMR 9002 CNRS-Université de Montpellier, Montpellier, France.
• ⁴ National Institutes of Health, Bethesda, MD 20892, USA.
• ⁵ Division of Pediatric Allergy and Immunology, Meram Medical Faculty, Necmettin Erbakan University, Konya, Turkey.
• ⁶ Department of Pediatric Allergy and Immunology, Ankara Children's Hematology Oncology Training and Research Hospital, Ankara, Turkey.
• ⁷ Department of Pediatrics, and Department of Internal Medicine, Division of Genetics, Endocrinology & Metabolism, University of Kansas Medical Center, Kansas City, KS 66215, USA.
• ⁸ Department of Pediatrics, Mansoura University Children's Hospital, Faculty of Medicine, Mansoura University, Egypt.
• ⁹ Department of Immunology-Histocompatibility, "Aghia Sophia" Children's Hospital, Athens, Greece.
• ¹⁰ Department of Pediatrics, Allergy and Clinical Immunology Unit, Royal Hospital, Muscat, Oman.
• ¹¹ Faculty of Medicine, Division of Pediatric Allergy and Immunology, Marmara University, Istanbul, Turkey.
• ¹² Department of Pediatrics, University of Washington, and Seattle Children's Research Institute, Seattle, WA 98101, USA.
• ¹³ Division of Transfusion Medicine, Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.
• ¹⁴ Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. Electronic address: raif.geha@childrens.harvard.edu.