Pediatric lymphangiography, thoracic duct embolization and thoracic duct disruption: a single-institution experience in 11 children with chylothorax

Pediatr Radiol. 2018 Feb;48(2):235-240. doi: 10.1007/s00247-017-3988-5. Epub 2017 Sep 28.

Abstract

Background: Interventional radiology treatment of chylothorax is well described in adults, with high technical and clinical success that decreases patient morbidity and mortality. However there is limited experience in children.

Objective: To report the technical and clinical success of lymphangiography, thoracic duct embolization and thoracic duct disruption in the pediatric population.

Materials and methods: We studied 11 pediatric patients (7 boys, 4 girls; median weight 6.0 kg) who underwent lymphangiography and thoracic duct embolization from November 2015 to May 2017. All 11 (100%) children presented with chylothorax, with 1 (9%) having concomitant chylous ascites and 1 (9%) having concomitant chylopericardium. Ten (91%) children had traumatic chylothorax and one (9%) had congenital chylothorax. We recorded technical success, clinical success and complications.

Results: Twelve procedures were completed in 11 children. Bilateral intranodal lymphangiography was technically successful in all (100%) patients. Central lymphatics were visualized in eight (67%) procedures. Access to central lymphatics was attempted in eight procedures and successful in five (63%). In three (37%) of the eight procedures, disruption was performed when the central lymphatics could not be accessed. Clinical success was achieved in 7/11 (64%) children. Three minor complications were reported. No major complications were encountered.

Conclusion: Lymphangiography, thoracic duct embolization and thoracic duct disruption are successful interventional strategies in children with chylothorax and should be considered as viable treatment options at any age.

Keywords: Children; Chylothorax; Embolization; Interventional radiology; Lymphangiography; Thoracic duct.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Chylothorax / congenital*
  • Chylothorax / diagnostic imaging
  • Chylothorax / therapy
  • Embolization, Therapeutic / methods*
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Lymphography
  • Male
  • Radiography, Interventional
  • Retrospective Studies
  • Thoracic Duct*
  • Treatment Outcome

Supplementary concepts

  • Chylothorax, congenital