The impact of individualised nutritional therapy according to DASH diet on blood pressure, body mass, and selected biochemical parameters in overweight/obese patients with primary arterial hypertension: a prospective randomised study

Kardiol Pol. 2018;76(1):158-165. doi: 10.5603/KP.a2017.0184. Epub 2017 Oct 5.

Abstract

Background and aim: The aim of the study was to assess the impact of individualised nutritional intervention based on the DASH diet (Dietary Approaches to Stop Hypertension) on the nutritional status, blood pressure, and selected biochemical parameters of obese/overweight patients with primary arterial hypertension.

Methods: A total of 131 participants were randomised to the DASH intervention group (DIG; n = 69, 33 males) or the control group (CG; n = 62, 32 males). A three-month nutritional intervention was carried out in the DIG group, while the control group received only standard recommendations. Body weight, height, waist and hip circumference, body composition, blood pressure, serum glucose, and insulin and leptin concentrations were measured at the baseline and after the intervention.

Results: Sixty-four (92.8%) participants in the intervention and 62 (100%) in the control group completed the study. In the DIG group a significant decrease in body mass, systolic and diastolic blood pressure, body fat content, fasting glucose, insulin, and leptin concentrations were observed in comparison to the control group (p < 0.05).

Conclusions: The DASH dietary intervention provides significant benefits to overweight/obese patients with primary hypertension.

Keywords: insulin resistance; nutritional therapy; obesity; primary arterial hypertension.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Aged
  • Blood Glucose
  • Blood Pressure
  • Body Composition
  • Dietary Approaches To Stop Hypertension*
  • Female
  • Humans
  • Hypertension / complications
  • Hypertension / diet therapy*
  • Insulin / blood
  • Leptin / blood
  • Male
  • Middle Aged
  • Overweight / blood
  • Overweight / complications
  • Overweight / diet therapy*
  • Prospective Studies

Substances

  • Blood Glucose
  • Insulin
  • Leptin