Approach to the Investigation and Management of Patients With Candida auris, an Emerging Multidrug-Resistant Yeast

Clin Infect Dis. 2018 Jan 6;66(2):306-311. doi: 10.1093/cid/cix744.

Abstract

Candida auris is an emerging, multidrug-resistant yeast that can spread in healthcare settings. It can cause invasive infections with high mortality and is difficult to identify using traditional yeast identification methods. Candida auris has been reported in more than a dozen countries, and as of August 2017, 112 clinical cases have been reported in the United States. Candida auris can colonize skin and persist in the healthcare environment, allowing for transmission between patients. Prompt investigation and aggressive interventions, including notification to public health agencies, implementation of contact precautions, thorough environmental cleaning and disinfection, infection control assessments, contact tracing and screening of contacts to assess for colonization, and retrospective review of microbiology records and prospective surveillance for cases at laboratories are all needed to limit the spread of C. auris. This review summarizes the current recommended approach to manage cases and control transmission of C. auris in healthcare facilities.

Keywords: Candida; communicable diseases; drug resistance; emerging; fungal; infection control; multiple.

Publication types

  • Review

MeSH terms

  • Antifungal Agents / therapeutic use
  • Candida / drug effects
  • Candida / isolation & purification*
  • Candidiasis / diagnosis*
  • Candidiasis / drug therapy*
  • Candidiasis / epidemiology
  • Candidiasis / microbiology
  • Communicable Diseases, Emerging / diagnosis
  • Communicable Diseases, Emerging / drug therapy
  • Communicable Diseases, Emerging / epidemiology
  • Communicable Diseases, Emerging / microbiology
  • Cross Infection / diagnosis
  • Cross Infection / drug therapy
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Disease Management*
  • Disease Transmission, Infectious / prevention & control
  • Drug Resistance, Multiple, Fungal
  • Humans
  • Infection Control / methods

Substances

  • Antifungal Agents