Silver and Palladium Cocatalyzed Carbonylative Activation of Benzotriazoles to Benzoxazinones under Neutral Conditions

Org Lett. 2017 Nov 17;19(22):6232-6235. doi: 10.1021/acs.orglett.7b03184. Epub 2017 Oct 26.

Abstract

A novel and efficient method for the carbonylative activation of benzotriazoles to benzoxazinones has been developed. By using a silver and palladium bimetallic catalyst system, a broad range of benzotriazoles were transformed into the corresponding benzoxazinones in moderate to good yields with excellent functional group tolerance. Notably, this procedure proceeds under neutral conditions.

Publication types

  • Research Support, Non-U.S. Gov't