Autoantibodies in immune thrombocytopenia affect the physiological interaction between megakaryocytes and bone marrow extracellular matrix proteins

Br J Haematol. 2018 Oct;183(2):319-323. doi: 10.1111/bjh.14977. Epub 2017 Oct 26.
No abstract available

Keywords: autoantibodies; extracellular matrix proteins; glycoproteins; immune thrombocytopenia; megakaryocytes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Autoantibodies / immunology*
  • Bone Marrow Cells / immunology*
  • Case-Control Studies
  • Cell Adhesion / immunology
  • Cells, Cultured
  • Extracellular Matrix Proteins / immunology*
  • Female
  • Humans
  • Male
  • Megakaryocytes / immunology*
  • Megakaryocytes / physiology
  • Middle Aged
  • Purpura, Thrombocytopenic, Idiopathic / immunology*
  • Thrombopoiesis / immunology
  • Young Adult

Substances

  • Autoantibodies
  • Extracellular Matrix Proteins