Can U Turn ILC2s Up?

Paul A Muller; Daniel Mucida

doi:10.1016/j.cell.2017.10.013

Can U Turn ILC2s Up?

Cell. 2017 Nov 2;171(4):742-744. doi: 10.1016/j.cell.2017.10.013.

Authors

Paul A Muller¹, Daniel Mucida²

Affiliations

¹ Laboratory of Mucosal Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA. Electronic address: pmuller@rockefeller.edu.
² Laboratory of Mucosal Immunology, The Rockefeller University, 1230 York Ave, New York, NY 10065, USA. Electronic address: mucida@rockefeller.edu.

PMID: 29100072
DOI: 10.1016/j.cell.2017.10.013

Abstract

Innate lymphoid cells (ILCs) are tuned to quickly respond to and amplify tissue-specific signals. Work of three independent groups in Nature uncovers a novel mode of inflammatory communication between ILC2s and neurons at mucosal surfaces.

Publication types

Comment

MeSH terms

Diabetes Mellitus, Type 2*
Humans
Immunity, Innate
Lymphocytes*
Neurons
Neuropeptides

Substances

Neuropeptides
neuromedin U

Grants and funding

F31 DK112601/DK/NIDDK NIH HHS/United States