Recent advances in diagnosis and treatment of cardiac amyloidosis

Yasuhiro Izumiya; Seiji Takashio; Seitaro Oda; Yasuyuki Yamashita; Kenichi Tsujita

doi:10.1016/j.jjcc.2017.10.003

Recent advances in diagnosis and treatment of cardiac amyloidosis

J Cardiol. 2018 Feb;71(2):135-143. doi: 10.1016/j.jjcc.2017.10.003. Epub 2017 Nov 5.

Authors

Yasuhiro Izumiya¹, Seiji Takashio², Seitaro Oda³, Yasuyuki Yamashita³, Kenichi Tsujita²

Affiliations

¹ Department of Cardiovascular Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan. Electronic address: izumiya@kumamoto-u.ac.jp.
² Department of Cardiovascular Medicine, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.
³ Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, Kumamoto, Japan.

PMID: 29113705
DOI: 10.1016/j.jjcc.2017.10.003

Abstract

Cardiac amyloidosis (CA) has been believed to be a rare disease for a long time, but recent sophisticated diagnostic modalities demonstrate that a considerable number of CA patients are hidden among those diagnosed with heart failure. Prognosis of CA was poor, but recent developments in therapeutic interventions have improved survival in these patients. Therefore, early detection and precise diagnosis is clinically important. In this review article, we overview recent progress in diagnosis and treatment for CA.

Keywords: Amyloidosis; Biomarker; Bone scintigraphy; Magnetic resonance imaging.

Publication types

Review

MeSH terms

Amyloidosis / diagnosis*
Amyloidosis / drug therapy*
Heart Diseases / diagnosis*
Heart Diseases / drug therapy*
Humans