Next-generation sequencing discriminates myelodysplastic/myeloproliferative neoplasms from paraneoplastic leukemoid reaction in cancer patients with hyperleukocytosis

MeSH terms

• Biomarkers, Tumor
• Bone Marrow / pathology
• DNA Mutational Analysis
• Diagnosis, Differential
• Gene Expression Profiling
• High-Throughput Nucleotide Sequencing
• Humans
• Leukemoid Reaction / diagnosis*
• Leukemoid Reaction / genetics*
• Leukemoid Reaction / mortality
• Leukocytosis / genetics*
• Leukocytosis / pathology*
• Mutation
• Myelodysplastic Syndromes / diagnosis*
• Myelodysplastic Syndromes / genetics*
• Myelodysplastic Syndromes / mortality
• Myeloproliferative Disorders / diagnosis*
• Myeloproliferative Disorders / genetics*
• Myeloproliferative Disorders / mortality
• Prognosis