Incidence and risk factors of hepatitis B virus reactivation in patients with multiple myeloma in an era with novel agents: a nationwide retrospective study in Japan

Yutaka Tsukune; Makoto Sasaki; Takeshi Odajima; Kazutaka Sunami; Tomomi Takei; Yukiyoshi Moriuchi; Masaki Iino; Atsushi Isoda; Aya Nakaya; Tsuyoshi Muta; Takaaki Miyake; Koji Miyazaki; Takayuki Shimizu; Kei Nakajima; Aiko Igarashi; Koji Nagafuji; Taro Kurihara; Tomonori Aoyama; Hiroki Sugimori; Norio Komatsu

doi:10.1038/s41408-017-0002-2

Incidence and risk factors of hepatitis B virus reactivation in patients with multiple myeloma in an era with novel agents: a nationwide retrospective study in Japan

Blood Cancer J. 2017 Nov 23;7(12):631. doi: 10.1038/s41408-017-0002-2.

Authors

Yutaka Tsukune¹, Makoto Sasaki², Takeshi Odajima³, Kazutaka Sunami⁴, Tomomi Takei⁵, Yukiyoshi Moriuchi⁶, Masaki Iino⁷, Atsushi Isoda⁸, Aya Nakaya⁹, Tsuyoshi Muta¹⁰, Takaaki Miyake¹¹, Koji Miyazaki¹², Takayuki Shimizu¹³, Kei Nakajima¹⁴, Aiko Igarashi¹⁵, Koji Nagafuji¹⁶, Taro Kurihara¹⁷, Tomonori Aoyama¹⁸, Hiroki Sugimori¹⁹, Norio Komatsu¹

Affiliations

¹ Department of Hematology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.
² Department of Hematology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan. msasaki@juntendo.ac.jp.
³ Faculty of Health Science, Daito Bunka University, School of Sports and Health Science, Higashi-Matsuyama, Saitama, 355-8501, Japan.
⁴ Department of Hematology, National Hospital Organization Okayama Medical Center, Okayama, Okayama, 701-1192, Japan.
⁵ Department of Hematology, Japanese Red Cross Medical Center, Shibuya-ku, Tokyo, 150-8935, Japan.
⁶ Department of Hematology, Sasebo City General Hospital, Sasebo, 857-0056, Nagasaki, Japan.
⁷ Department of Hematology, Yamanashi Prefectural Central Hospital, Kofu, Yamanashi, 400-8506, Japan.
⁸ Department of Hematology, National Hospital Organization Shibukawa Medical Center, Shibukawa, Gunma, 377-0280, Japan.
⁹ First Department of Internal Medicine, Kansai Medical University, Hirakata, Osaka, 573-1010, Japan.
¹⁰ Department of Hematology/Oncology, Japan Community Health Care Organization Kyushu Hospital, Kita-Kyusyu, Fukuoka, 806-8501, Japan.
¹¹ Department of Oncology/Hematology, Shimane University Hospital, Izumo, Shimane, 693-8501, Japan.
¹² Department of Transfusion and Cell Transplantation, Kitasato University School of Medicine, Sagamihara, Kanagawa, 252-0374, Japan.
¹³ Division of Hematology, Department of Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582, Japan.
¹⁴ Department of Hematology/Oncology, University of Yamanashi, Chuo, Yamanashi, 409-3898, Japan.
¹⁵ Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Bukyo-ku, Tokyo, 113-8677, Japan.
¹⁶ Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Fukuoka, 830-0011, Japan.
¹⁷ Department of Internal Medicine, Niigata Cancer Center Hospital, Niigata, Niigata, 951-8566, Japan.
¹⁸ Department of Gastroenterology, Juntendo University School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.
¹⁹ Department of Preventive Medicine, Daito Bunka University, Graduate School of Sports and Health Science, Higashi-Matsuyama, Saitama, 355-8501, Japan.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Antineoplastic Agents / adverse effects
Female
Hematopoietic Stem Cell Transplantation / adverse effects
Hepatitis B / epidemiology*
Hepatitis B virus / physiology
Humans
Incidence
Japan
Male
Middle Aged
Multiple Myeloma / therapy
Multiple Myeloma / virology*
Retrospective Studies
Risk Factors
Transplantation, Autologous
Virus Activation*

Substances

Antineoplastic Agents