The wearable cardioverter defibrillator as a bridge to reimplantation in patients with ICD or CRT-D-related infections

J Cardiothorac Surg. 2017 Nov 25;12(1):99. doi: 10.1186/s13019-017-0669-2.

Abstract

Background: The approach to treat device infection in patients with implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy defibrillator (CRT-D) is a challenging procedure. Optimal treatment is complete extraction of the infected device. To protect these patients from sudden cardiac arrest while waiting for reimplantation and to avoid recurrent infection, a wearable cardioverter defibrillator (WCD) seems to be a valuable solution. Therefore, we investigated the management and outcome of patients with ICD or CRT-D infections using the WCD as a bridge to re-implantation after lead extraction procedures.

Methods: We conducted a retrospective study on consecutive patients who underwent ICD or CRT-D removal due to device-related local or systemic infections. All patients were prescribed a WCD at our center between 01/2012 and 10/2015. All patients returned to our outpatient clinic for regular ICD or CRT-D monitoring initially 1 and 3 months after reimplantation followed by 6-months intervals.

Results: Twenty-one patients (mean age 65.0 ± 8.0 years, male 76.2%) were included in the study. Complete lead extraction was achieved in all patients. While waiting for reimplantation one patient experienced a symptomatic episode of sustained ventricular tachycardia. This episode was converted successfully into sinus rhythm by a single 150 J shock. Mean follow-up time 392 ± 206 days, showing survival rate of 100% and freedom from reinfection in all patients.

Conclusion: The WCD seems to be a valuable bridging option for patients with ICD or CRT-D infections, showing no recurrent device infection.

Keywords: CIED-infection; ICD infection; Lead/ device extraction; Sudden cardiac arrest; Ventricular tachycardia; Wearable cardioverter defibrillator.

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Death, Sudden, Cardiac / prevention & control*
  • Defibrillators, Implantable*
  • Device Removal
  • Electric Countershock / instrumentation*
  • Electrocardiography
  • Female
  • Germany / epidemiology
  • Humans
  • Incidence
  • Male
  • Prosthesis-Related Infections / epidemiology*
  • Prosthesis-Related Infections / etiology
  • Prosthesis-Related Infections / therapy
  • Replantation
  • Retrospective Studies
  • Survival Rate / trends
  • Tachycardia, Ventricular / physiopathology
  • Tachycardia, Ventricular / therapy*

Substances

  • Anti-Bacterial Agents