Recognition of self-DNA drives cardiac inflammation: why broken hearts fail

Nat Med. 2017 Dec 7;23(12):1400-1401. doi: 10.1038/nm.4455.

Authors

Kory J Lavine^{1

2}, Douglas L Mann¹

Affiliations

¹ Center for Cardiovascular Research, Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
² Departments of Developmental Biology and of Immunology and Pathology, Washington University School of Medicine, St. Louis, Missouri, USA.

PMID: 29216037
DOI: 10.1038/nm.4455

No abstract available

Publication types

Comment

MeSH terms

DNA
Heart
Humans
Inflammation / genetics
Interferon Regulatory Factor-3
Interferon Type I*
Myocardial Infarction*

Substances

IRF3 protein, human
Interferon Regulatory Factor-3
Interferon Type I
DNA