HIV+ deceased donor referrals: A national survey of organ procurement organizations

Clin Transplant. 2018 Feb;32(2):10.1111/ctr.13171. doi: 10.1111/ctr.13171. Epub 2018 Jan 16.

Abstract

Background: HIV-infected (HIV+) donor organs can be transplanted into HIV+ recipients under the HIV Organ Policy Equity (HOPE) Act. Quantifying HIV+ donor referrals received by organ procurement organizations (OPOs) is critical for HOPE Act implementation.

Methods: We surveyed the 58 USA OPOs regarding HIV+ referral records and newly discovered HIV+ donors. Using data from OPOs that provided exact records and CDC HIV prevalence data, we projected a national estimate of HIV+ referrals.

Results: Fifty-five (95%) OPOs reported HIV+ referrals ranging from 0 to 276 and newly discovered HIV+ cases ranging from 0 to 10 annually. Six OPOs in areas of high HIV prevalence reported more than 100 HIV+ donor referrals. Twenty-seven (47%) OPOs provided exact HIV+ referral records and 28 (51%) OPOs provided exact records of discovered HIV+ cases, totaling 1450 HIV+ referrals and 39 discovered HIV+ donors in the prior year. These OPOs represented 67% and 59% of prevalent HIV cases in the USA; thus, we estimated 2164 HIV+ referrals and 66 discovered HIV+ cases nationally per year.

Conclusions: OPOs reported a high volume of HIV+ referrals annually, of which a subset will be medically eligible for donation. Particularly in areas of high HIV prevalence, OPOs require ongoing support to implement the HOPE Act.

Keywords: HIV; deceased donors; organ transplantation; public health.

MeSH terms

  • Donor Selection*
  • Follow-Up Studies
  • HIV / isolation & purification
  • HIV Infections / virology*
  • Humans
  • Organ Transplantation / standards*
  • Prognosis
  • Referral and Consultation*
  • Tissue Donors / legislation & jurisprudence
  • Tissue Donors / statistics & numerical data*
  • Tissue and Organ Procurement / classification
  • Tissue and Organ Procurement / legislation & jurisprudence
  • Tissue and Organ Procurement / organization & administration*