Resistance training-induced decrease in central arterial compliance is associated with decreased subendocardial viability ratio in healthy young men

Appl Physiol Nutr Metab. 2018 May;43(5):510-516. doi: 10.1139/apnm-2017-0449. Epub 2017 Dec 18.

Abstract

High-intensity resistance training decreases central arterial compliance (CAC). Subendocardial viability ratio (SEVR) is a useful tool that reflects the balance between coronary perfusion and left ventricular afterload. Animal studies have demonstrated that decreased CAC is associated with SEVR deterioration. Therefore, resistance training-induced decrease in CAC may be associated with changes in SEVR. The objective of the present study was to investigate the association between SEVR and CAC using both cross-sectional and longitudinal (i.e., resistance training) study designs. To achieve this, we first conducted a cross-sectional study to investigate the association between SEVR and CAC in 89 young men. Thereafter, a longitudinal study was performed to examine the effects of resistance training on SEVR and CAC in young men. A total of 28 young men were divided into 2 groups: control (n = 13) and training (n = 15). In the training group, subjects underwent supervised resistance training for 4 weeks (5 sets of 10 repetitions at 75% of 1-repetition maximum, 3 times/week). CAC and SEVR were then measured in all subjects. In the cross-sectional study, SEVR was significantly positively correlated with CAC, whereas resistance training significantly decreased both SEVR and CAC. Moreover, training-induced changes in CAC were significantly correlated with changes in SEVR. Thus, these results suggest that resistance training-induced decrease in CAC is associated with decreased SEVR in young men.

Keywords: arterial distensibility; artère carotide; capacité de dilatation artérielle; carotid artery; cross-sectional study; hemodynamics; hémodynamique; longitudinal study; étude longitudinale; étude transversale.

MeSH terms

  • Adult
  • Arterial Pressure
  • Body Composition
  • Cardiovascular Diseases / physiopathology
  • Carotid Arteries / physiopathology*
  • Compliance
  • Cross-Sectional Studies
  • Endocardium / physiopathology*
  • Exercise
  • Humans
  • Longitudinal Studies
  • Male
  • Pulse Wave Analysis
  • Resistance Training*
  • Sample Size
  • Young Adult